Alpha GPC Capsules
The Best Choline Supplement That Crosses Blood-Brain Barrier
Supports brain cognition and promotes learning and memory
Alpha GPC is a nootropic that has been shown to:
- support cognition and mental performance
- promote memory and learning in healthy individuals
- boost your focus (even in stressful situations)
Scientific studies indicate that Alpha GPC is a very efficient dietary supplement to get the powerful molecule choline through your diet, into your blood and brain.
Once absorbed, it turns into acetylcholine - the learning neurotransmitter - leading to a whole range of cognitive enhancing properties.
"There is no question this improves memory. It's amazing! Using now for a year."
- J. Slimak
Enhanced Brain Function, Memory and Learning
The powerful learning neurotransmitter acetylcholine plays a vital role in your memory, nervous system and muscle control.
Taking Alpha GPC regularly may boost this neurotransmitter, and:
- enhance your brain function
- promote memory
- increase alertness (and prevent mental fatigue)
- boost your levels of focus
It’s a great supplement, backed by science, that may help you take your mental performance to the next level.
Powerful Source Of Nutrients For Brain Health
Alpha GPC is the only choline source that can easily cross the blood-brain barrier, thereby making it the preferred source of choline for your brain health.
Our Alpha GPC capsules contain a dose of 325mg compared to only 300 mg per capsule of our competitors, making it the highest dose of choline available on the market. Plus, it contains no artificial fillers, for optimal results.
Safe & Effective
VitaMonk's products are formulated by licensed doctors and manufactured in state-of-the-art facilities following strict GMP compliance standards.
We go to great lengths to make sure our supplements meet the highest safety standards. When you use our supplements, you KNOW that you’ll only get the highest quality ingredients that have the most scientific backing to help you get results.
60 Day Money-Back Guarantee
We are so confident that you'll love this product that it comes with a 100% money back guarantee. If for any reason you’re not completely satisfied with this supplement after using it, just let us know.
Scientific References & Further Reading
Alpha GPC Choline Overview:
Alpha GPC Choline Overview:
- Helps improve focus, memory, and cognition
- Supports healthy cognition, particularly in the elderly
- Often used as a nootropic
- Confers neuroprotective traits
- Enhances power output
Supplementation with choline is beneficial for whole body metabolism and is reported to increase power output. However, it is its cognitive enhancing properties that have made Alpha GPC (Alpha-glycerophosphocholine or α-GPC) of great interest to the world of nootropics.
Typically, 40% of Alpha-GPC’s weight is converted into choline within the body. This makes Alpha-GPC the most bioavailable dietary form of choline available.
In addition to supporting healthy cognition and increasing mental performance, supplementation with Alpha-GPC has been linked with increases in power output, iron absorption, fat oxidation, and iron absorption.
Choline is involved in numerous biological functions, such as nerve impulse transmission, cell signaling, structural integrity of cell membranes, and lipid transport and metabolism. As it is essential for correct bodily function, choline is commonly referred to as a Pseudovitamin.
Choline undergoes irreversible metabolism into trimethylglycine (TMG) in the mitochondria. This reaction is catalyzed by the enzyme betaine aldehyde dehydrogenase. During neurotransmission, the enzyme choline acetyltransferase converts choline into acetylcholine.
Choline is metabolically interrelated to folate. If there is a shortage of folate in the body then this can be offset by using choline as an alternative methyl donor.
Many people are likely to be at risk of choline deficiency, especially endurance athletes and people who drink excessive amounts of alcohol.
In a study carried out by the Institute of Medicine of the National Academies, ninety percent of Americans were found to have choline intake levels at less than the considered adequate intake (AI: 425g mg/day women; 550 mg/day men).
Choline deficiency can lead to liver damage from a condition known as fatty liver.
Brain Cognition and Memory
Any compound capable of increasing levels of acetylcholine in the brain is known as a cholinergic.
There are two main classes of cholinergics: those that provide the body with choline, such as Alpha-GPC; and those that inhibit acetylcholine breakdown.
The Most Effective Dietary Cholinergic
Alpha-GPC, an intermediate in lecithin metabolism and a metabolite of phosphatidylcholine (PC), is currently considered the most effective cholinergic. Its consumption results in greater levels of choline in the plasma and brain than seen when taking choline or CDP-choline powder supplements.
Levels of Alpha-GPC uptake in the brain spike between 1 to 3 hours after oral ingestion, with positive influences observed for 24 hours.
Alpha-GPC Confers Neuroprotective Traits
As an efficient prodrug, Alpha GPC is able to confer dietary choline to the body when taken orally.
It is very likely that Alpha-GPC confers neuroprotective traits. It is thought to do this by increasing brain acetylcholine levels in the frontal cortex and through facilitating high-affinity uptake of choline at the hippocampus.
There is also a reported increase in the secondary release of GABA at Alpha-1 adrenergic receptors. GABA, alongside glutamate, plays a major role in the mediation of brain activity.
Increases Focus under Stressful Conditions
Alpha-GPC is able to enhance a person’s ability to focus and pay better attention to detail under stressful conditions when it is consumed alongside phosphatidylserine and caffeine.
Promotes Memory Formation and Recall
Alpha-GPC is able to promote memory formation effects through translocation of Protein kinase C (PKC) in the cortex of rats. Furthermore, passive and active learning abilities were found to be enhanced in healthy rats.
Alpha-GPC may help to support cognitive function and the formation of memories. The levels of these improvements are likely to be greater than what is reported to when supplementing with CDP-choline.
Improvements in memory formation, retention, and focus allow one’s brain to improve its problem-solving abilities and to recall memories at a much greater pace. Thus Alpha-GPC has many potential mental health performance benefits in healthy individuals.
Increases in Brain Phospholipid Synthesis and Enhanced Iron Absorption
Choline is a prodrug of Uridine (also available from VitaMonk). Uridine monophosphate nucleotide is able to increase levels of phospholipid synthesis in the brain, which in turn can lead to a greater concentration of glycerophosphocholine levels in adults.
Alpha-GPC has also been linked with facilitating absorption of non-heme iron from foods, doing so with a comparable potency to Vitamin C.
Take With: It is recommended that choline supplements be taken alongside Vitamin B2 (Riboflavin) products as this can mask the fishy smell that is sometimes prevalent when people take choline supplementation.
 LINUS PAULING INSTITUTE: Micronutrient Information Center [http://lpi.oregonstate.edu/mic/other-nutrients/choline]
 Zeisel and da Costa. Choline: An Essential Nutrient for Public Health. Nutr Rev. 2009 Nov; 67(11): 615–623. doi: 10.1111/j.1753-4887.2009.00246.x
 Tayebati et al. Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain. CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):94-103.
 Lopez et al. Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine. Pharmacol Biochem Behav. 1991 Aug;39(4):835-40.
 Ferraro et al. Evidence for an in vivo and in vitro modulation of endogenous cortical GABA release by alpha-glycerylphosphorylcholine. Neurochem Res. 1996 May;21(5):547-52.
 Hoffman et al. The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students. J Int Soc Sports Nutr. 2010 Dec 15;7:39. doi: 10.1186/1550-2783-7-39
 Govoni et al. PKC translocation in rat brain cortex is promoted in vivo and in vitro by alpha-glycerylphosphorylcholine, a cognition-enhancing drug. Ann N Y Acad Sci. 1993 Sep 24;695:307-10.
 Ziegenfuss et al. Acute supplementation with alpha-glycerylphosphorylcholine augments response to, and peak force production during, resistance exercise. Journal of the International Society of Sports Nutrition 20085(Suppl 1):P15 DOI: 10.1186/1550-2783-5-S1-P15
Further Citations Related to Alpha GPC
- Bellar et al. The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength. J Int Soc Sports Nutr. 2015 Nov 17;12:42. doi: 10.1186/s12970-015-0103-x.
- Kidd PM. Neurodegeneration from mitochondrial insufficiency: nutrients, stem cells, growth factors, and prospects for brain rebuilding using integrative management. Altern Med Rev. 2005 Dec;10(4):268-93.
What is the Dosage of Alpha GPC VitaMonk
Each VitaMonk Alpha GPC capsule provides 325 mg of L-alpha glycerophosphocholine. We prefer easy to swallow capsules instead of more difficult tablets or bulk powders. All of our products also use vegicaps, so they are vegetarian and gluten free.
Can you take Alpha GPC with food?
Yes, you can take it with or without food.
What are some of the reasons people take Alpha GPC?
There is a myriad of reasons, and several different use cases in which someone might take Alpha-GPC. Here is a list of some of the more common uses based on anecdotal evidence:
- Enhance focus and concentration
- To maintain high choline levels when taking a racetam (aniracetam, piracetam, oxiracetam, pramiracetam)
- To help you relax
- Improves dreaming
- For energy
- Weight loss
- For studying
- For strength Basically...
Choline helps with a laundry list of items
How long does it take to work?
Alpha GPC really isn't meant to be a "quick fix" product. However, it is absorbed quickly, and its positive benefits start kicking in within an hour.
What is it commonly taken with?
There are a bunch of different possibilities, and many individuals have their own stacks that work best for them. You should always talk to your doctor first about this, but here are a few of the more common combinations frequently mentioned on Reddit, Examine and WebMD.
- With Omega 3: (Fish Oil, Krill oil)
- With the Racetams (Aniracetam, Piracetam, Oxiracetam, Pramiracetam)
- With Uridine
- With Noopept
- Citicoline for a choline stack
- ALCAR (Acetyl L Carnitine)
How Much Alpha GPC Should I Take Daily?
We must always say to take the recommended dose suggested by your doctor. With that said people usually take between 300 mg to 1200 mg per day. How much should I take with:
- with Aniracetam: between 300mg - 1200mg a day
- with Piracetam: between 300mg - 1200mg a day
- with Noopept: between 300mg - 1200mg a day
with Pramiracetam: between 300mg - 1200mg a day
Where to buy Alpha GPC?
You should purchase from VitaMonk of course! We also sell on Amazon with fantastic reviews. You can safely purchase online from us using all major credit cards, Paypal and Bitcoin.