Pterostilbene
Pterostilbene VitaMonk
Natural Antioxidant
Pterostilbene 150mg Bottle
Pterostilbene Capsules
Pterostilbene
Pterostilbene VitaMonk
Natural Antioxidant
Pterostilbene 150mg Bottle
Pterostilbene Capsules

Pterostilbene Capsules

$14.24

Ever heard people say blueberries and red wine are healthy for you? That’s because they’re a source of (trans-)pterostilbene - a naturally occurring molecule that can be a powerful way to:

  • Promote healthy brain cells (and overall brain health)
  • Support healthy cognitive functions, memory and motor functions
  • Repair DNA (acting as a 100% natural antioxidant)
  • Promote healthy blood sugar levels & blood circulation
  • Promote healthy arteries and veins

Supplementing your diet with pterostilbene can pack a potent nutritional punch, promoting healthy aging, longevity and quality of life.

Supplement Facts:

  • Serving Size: 1 Capsule
  • Servings Per Container: 60 
  • Amount Per Serving: 50mg or 100mg or 150mg (depending on bottle purchased)
  • Other Ingredients: Vegetable capsule shell (Hydroxypropyl Methylcellulose), Titanium Dioxide

100% Natural Antioxidant (Supporting DNA Repair and Healthy Circulation)

The antioxidant properties of pterostilbene have been scientifically documented to support healthy cellular function in both your brain and your body.

It provides a healthy response to oxidative stress within your cells, thereby protecting your DNA from free radical damage

These antioxidants also promote healthy arteries and veins - giving you a strong circulatory system you can rely on.

Pterostilbene Capsules

Support Cognition and Mood

Multiple studies have observed pterostilbene’s link to support memory and motor function.

Some scientists even believe that pterostilbene has the potential to promote healthy dopamine levels in the brain - which can help improve your mood, boost your memory and accelerate learning.

Pterostilbene Capsules

Healthy Blood Sugar & Triglyceride Levels

Taking pterostilbene may also support normal glucose and triglyceride levels in healthy individuals.

Through expressing essential proteins, this can regulate your cellular differentiation, development and metabolism.

Pterostilbene Capsules

Safe, and Effective

VitaMonk's products are formulated by licensed doctors and manufactured in state-of-the-art facilities following strict GMP compliance standards.

We go to great lengths to make sure our supplements meet the highest safety standards. When you use our supplements, you KNOW that you’ll only get the highest quality ingredients that have the most scientific backing to help you get results.

Pterostilbene Capsules
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Pterostilbene Overview 

Pterostilbene is an antioxidant with a similar structure to Resveratrol. It is thought to have beneficial supporting effects related to cognition, blood sugar levels, cell damage, the cardiovascular system, longevity, the muscular system, weight loss, and healthy inflammatory response. As an antioxidant it plays an important role in supporting healthy response to DNA damage. 

The full chemical name for Pterostilbene is trans-3,5-dimethoxy-4-hydroxystilbene.

The common name for this substance is derived from the genus of plants (Pterocarpus) from which it was first discovered. This plant based compound is naturally found in the heartwoods of Pterocarpus species such as Sandalwood and the Indian Kino tree, and is also naturally found in grape leaves, blueberries, peanuts, almonds, the roots of false rhubarb, and in the house-plant Dracaena. Like many other stilbenes it plays a natural role in plant defense.

The numerous health benefits associated with Pterostilbene supplementation are mainly accredited to its antioxidant properties. These and other factors help to improve and correct normal cell function.

Some of the main biological effects of Pterostilbene include:

  • Reduction in Oxidative stress (OS)
  • Production of reactive oxygen species (ROS; e.g., hydrogen peroxide and superoxide anion) important in pathogenesis
  • Increased antioxidant capabilities
  • Increased expression of glutathione, glutathione reductase, and glutathione peroxidase
  • Increased induced expression of catalase and superoxide dismutase (SOD)

Pterostilbene is chemically similar to resveratrol (also available from VitaMonk). Resveratrol is found in red wine and is thought to be associated with many of the health given properties that are often linked to consumption of the beverage.

Pterostilbene portrays an advantage over resveratrol in that it is more readily absorbed into the body following oral digestion (giving improved bio-availability and activity) [1].

Along with piceatannol, these antioxidants belong to a group of dietary compounds known as stilbenes. Pterostilbene has a greater bioavailability than other stilbenes (close to 4-fold as much as resveratrol), and thus has enhanced dietary benefits. These are thought to contribute to its reported supportive effects.

Brain Function and Health

Pterostilbene is strongly linked to three main neurological benefits:

  • Support of neurological function
  • Enhancing mood
  • Supporting memory and learning

Thus like other neurological associated products, such as Alpha-GPC and Uridine Monophosphate, it may be beneficial for supporting brain cognition.

Pterostilbene is thought to have a more potent effect on neuroinflammation than resveratrol. It has been demonstrated that 10 to 30 micromolar may reduce lipopolysaccharide induced nitric oxide (NO) production in microglia [2]. 

Pterostilbene has been demonstrated to improve mental actions and processes in animals such as rats over a ~3 month period. These improvements were correlated to increased concentration of the compound in the hippocampus [3]. 

It has been reported that Pterostilbene has an impact upon ERK phosphorylation in the hippocampus. It can therefore improve mood and support normal response to anxiety.

Inflammatory Response and Immunological Aspects  

As it is much more bio-available, pterostilbene likely provides a much greater inflammatory response effect at lower concentrations when taken orally than has been reported for resveratrol. It is thought that the main cause of this greater action is due to indirect antioxidant effects.

Healthy Aging

In elderly people a progressive decline in antioxidant activity caused by oxidative stress is one of the main mechanisms for age-related deterioration of cognition and motor function.

There have been numerous studies that have demonstrated blueberry extract (rich in the antioxidant Pterostilbene) may support dopamine control of known neuro-degeneration related markers. 

Pterostilbene is possibly able to modify the expression levels of numerous important mitochondrial genes and may reduce the effects of oxidative stress observed during neuronal aging processes [4]. 

The mitochondria are known as the powerhouses of the cell as they are involved in the creation of energy in the form of ATP. It has been reported that Pterostilbene can support mitochondrial depolarization.

Impact on the Cardiovascular System

Pterostilbene is reported to support healthy blood pressure levels and studies using blueberries suggest that activation of antioxidant enzymes may lead to protective benefits for the cardiovascular system [5, 6].

There are mixed results of Pterostilbene intake and its impact on cholesterol. It has been reported that it may be a PPARα ligand. In hamsters, consumption of pterostilbene supported better levels of ‘bad’ LDL-Cholesterol and ‘good’ HDL-Cholesterol [7]. Conversely, it has been reported that cholesterol levels were negatively affected in people who already have high LDL-cholesterol levels [6]. 

Interestingly, there was a correlated weight-loss observed with supplementation of Pterostilbene; neither weight-loss or support of HDL-cholesterol levels occurred when taken alongside grape seed extract (GSE). GSEs are also rich in antioxidants and are reported to support estrogen excess and an ability to enhance blood flow in healthy individuals.

If you are an healthy individual wishing to maintain healthy cholesterol levels you may wish to take a look at the POLICOSANOL product, which is also available for sale online at VitaMonk and on our Amazon store.

Supplementation with pterostilbene may also support healthy levels of serum triglycerides in rats with high blood sugar levels.

When Pterostilbene is supplemented alongside an extended-release of caffeine there is an observable benefit in resistance training-induced skeletal muscle. This occurs with no adverse affects on blood chemistry [8].

Further Reading

  • Examine: A look at a more potent dimethylated derivative of resveratrol [https://examine.com/supplements/Pterostilbene] 
  • Reddit Stack Advise: Does Pterostilbene have the potential to be considered a nootropic? [https://www.reddit.com/r/StackAdvice/comments/54v2bf/should_we_consider_pterostilbene_as_a_potential/]
  • Quora: Compare experiences and dosage models of using pterostilbene’s. [https://www.quora.com/What-are-your-experiences-with-pterostilbene-reservatrol-or-both-combined-Which-dosage-are-you-taking]
  • WebMD: Nutrients That Work Better Together; Diet Findings [http://www.webmd.com/food-recipes/features/food-synergy-nutrients-that-work-better-together#1]

Citations, References, and Reviews 

[1] Kapetanovic et al. Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol. 2011 Sep;68(3):593-601. doi: 10.1007/s00280-010-1525-4.

[2] Carey et al. Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia. J Agric Food Chem. 2013 Jun 26;61(25):5979-86. doi: 10.1021/jf400342g dm m 

[3] Al Rahim et al. Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation. Planta Med. 2013 Jun;79(9):723-30. doi: 10.1055/s-0032-1328553. 

[4] Joseph. Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging. J Agric Food Chem. 2008 Nov 26;56(22):10544-51. doi: 10.1021/jf802279h.

[5] Rimando et al. Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem. 2005 May 4;53(9):3403-7.

[6] Riche et al. Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial. Evid Based Complement Alternat Med. 2014;2014:459165. doi: 10.1155/2014/459165

[7] Rimando et al. Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem. 2005 May 4;53(9):3403-7. 

[8] Joy et al. Twelve weeks supplementation with an extended-release caffeine and ATP-enhancing supplement may improve body composition without affecting hematology in resistance-trained men. J Int Soc Sports Nutr. 2016 Jun 10;13:25. doi: 10.1186/s12970-016-0136-9.

Further references used and compared in the significant research of this article

Estrela et al. Pterostilbene: Biomedical applications. Crit Rev Clin Lab Sci. 2013 May-Jun;50(3):65-78. doi: 10.3109/10408363.2013.805182 

Poulose et al. Effects of pterostilbene and resveratrol on brain and behaviour. Neurochemistry International, Volume 89, October 2015, Pages 227–233

What is pterostilbene thought to affect?

Pterostilbene may promote healthy plasma insulin and thus support healthy levels of blood glucose. It also reduces oxidative stress, HbA1c, glucose-6-phosphatase, and Fructose-1, 6-biphosphatase. While GSH, GST, SOD, GPx, catalase, and hexokinase are all thought to be increased.

Does pterostilbene have any neurological brain boosting effects? 

Rodents given pterostilbene supplements were observed to have increased maze performance, cognitive performance, MnSOD, and PPAR-α; there was an associated decrease in phosphorylated JnK and tau.

What is the natural role of pterostilbene? Where does it come from?

It is a plant phytoalexin. It contains antioxidants and substances that support a healthy response to microbes, which in turn play a major role in plant defense. 

What are the main benefits of Pterostilbene?

The health benefits are largely associated with its antioxidant activity, and are thus likely to be vast. 

Does pterostilbene have health benefit effects during aging? 

Yes, Pterostilbene has been seen to promote healthy aging in various animals and in yeast.

How does Pterostilbene help to protect the brain?

By direct and indirect activation of signaling pathways that play a role in protecting and restoration of neurons from oxidative stress and inflammation.

Pterostilbene vs Resveratrol

Although pterostilbene is more bioavailable than the closely related resveratrol, at the current time much more is known about the health benefits and the functions and activities of the latter. You’ll be glad to know that in addition to this product that VitaMonk also produces a combined supplement that contains both RESVERATROL AND PTEROSTILBENE.

What about combining Pterostilbene and Nicotinamide riboside?

Nicotinamide riboside is a form of vitamin B3 that is a precursor of NAD+. Research that used both of these compounds (vitamins) concurrently showed that NAD+ levels were better supported.

What is Pterostilbene and caffeine used for?

The combination of these two pharmaceuticals has been shown to be of benefit to skeletal muscle in resistance-trained subjects.

Does it act as a remedy to relieve everything?

No, Pterostilbene supplements and similar are natural supplements that increase antioxidant activities, it is not one of those treat and cure all relief remedies fed as gospel by the newspapers.

What foods contain Pterostilbene? 

It appears to be present at low concentrations in multiple berries eg., blueberries, and almonds and peanuts. 

Where can I buy Pterostilbene near me? 

You can purchase the best Pterostilbene on sale at the top supplement store VitaMonk; for sale online right here and on Amazon. 

How many Capsules are in a container?

60 capsules. This provides a one to two month supply dose for adults, both men and women, depending upon how many times per day they take the product.

What does each tablet/pill contain?

Capsules come in three different dosages, either containing 50 mg, 100 mg, or 150 mg of Trans-Pterostilbene powder. Other ingredients include Vegetable cellulose (capsule) and Rice flour.

How can I learn more about the parts of the human body that I have issues with?

If you would like to learn more about things like the Prostate, liver, colon, vascular, and proliferation and pancreatic issues are treated then the content provided by the WebMD colleagues are a great place to start.

Pterostilbene, how much to take?

It is recommended to take the product daily for maximal health benefits. 

Are VitaMonk supplement capsules, tablets, and pills suitable for vegetarians and seniors?

Yes, our gluten free herb vegicaps are suitable for vegetarians.

What are the shipping costs?

Free shipping is available on orders of $35 or more.